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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPNPEP3 All Species: 16.06
Human Site: S229 Identified Species: 35.33
UniProt: Q9NQH7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQH7 NP_071381.1 507 57034 S229 L T E A K A K S K N K V R G V
Chimpanzee Pan troglodytes XP_515152 507 56971 S229 L T E A K A K S K N K V R G V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538358 507 57092 S229 L T E V K A R S K N K V R A V
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508206 540 60603 S262 L T E T K A R S K N R V R G L
Chicken Gallus gallus XP_416240 502 56268 S229 R S K N H I Q S I R H L V Q N
Frog Xenopus laevis NP_001086945 502 56377 S229 R S K N R I R S L R H L V Q Q
Zebra Danio Brachydanio rerio NP_996962 510 56616 V233 L L E G G Q L V K S L R P L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608376 545 60861 P254 L S G N Q Q R P L L P A Y T F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793902 510 57147 N230 N L V T P C R N K G H A V N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172401 493 54963 G230 S A S I A C Q G L L K T M L H
Baker's Yeast Sacchar. cerevisiae P40051 511 57971 I231 N S I A N K T I K P I S K R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 92.9 N.A. N.A. N.A. N.A. 77.9 78.1 67 57.2 N.A. 34.3 N.A. N.A. 50.7
Protein Similarity: 100 99.6 N.A. 96.4 N.A. N.A. N.A. N.A. 86.4 88.9 82 73.3 N.A. 55.5 N.A. N.A. 68
P-Site Identity: 100 100 N.A. 80 N.A. N.A. N.A. N.A. 73.3 6.6 6.6 20 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 93.3 33.3 40 26.6 N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 37.6 34 N.A.
Protein Similarity: N.A. N.A. N.A. 57.7 54.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 28 10 37 0 0 0 0 0 19 0 10 0 % A
% Cys: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 10 10 10 0 0 10 0 10 0 0 0 28 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 28 0 0 0 10 % H
% Ile: 0 0 10 10 0 19 0 10 10 0 10 0 0 0 19 % I
% Lys: 0 0 19 0 37 10 19 0 64 0 37 0 10 0 0 % K
% Leu: 55 19 0 0 0 0 10 0 28 19 10 19 0 19 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 19 0 0 28 10 0 0 10 0 37 0 0 0 10 10 % N
% Pro: 0 0 0 0 10 0 0 10 0 10 10 0 10 0 0 % P
% Gln: 0 0 0 0 10 19 19 0 0 0 0 0 0 19 10 % Q
% Arg: 19 0 0 0 10 0 46 0 0 19 10 10 37 10 0 % R
% Ser: 10 37 10 0 0 0 0 55 0 10 0 10 0 0 0 % S
% Thr: 0 37 0 19 0 0 10 0 0 0 0 10 0 10 10 % T
% Val: 0 0 10 10 0 0 0 10 0 0 0 37 28 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _